{"id":3619,"date":"2024-10-28T14:00:15","date_gmt":"2024-10-28T06:00:15","guid":{"rendered":"https:\/\/www.transplantation.com.cn\/?p=3619"},"modified":"2025-04-01T17:53:12","modified_gmt":"2025-04-01T09:53:12","slug":"%e4%be%9b%e8%80%85%e7%89%b9%e5%bc%82%e6%80%a7treg%e7%bb%86%e8%83%9e-%e8%82%be%e7%a7%bb%e6%a4%8d%e5%85%8d%e7%96%ab%e8%80%90%e5%8f%97%e7%9a%84%e6%96%b0%e6%80%9d%e8%b7%af","status":"publish","type":"post","link":"https:\/\/www.transplantation.com.cn\/zh_CN\/2024\/10\/28\/%e4%be%9b%e8%80%85%e7%89%b9%e5%bc%82%e6%80%a7treg%e7%bb%86%e8%83%9e-%e8%82%be%e7%a7%bb%e6%a4%8d%e5%85%8d%e7%96%ab%e8%80%90%e5%8f%97%e7%9a%84%e6%96%b0%e6%80%9d%e8%b7%af\/","title":{"rendered":"\u4f9b\u8005\u7279\u5f02\u6027Treg\u7ec6\u80de\u2014\u2014\u80be\u79fb\u690d\u514d\u75ab\u8010\u53d7\u7684\u65b0\u601d\u8def"},"content":{"rendered":"\n<figure class=\"wp-block-image aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"688\" height=\"134\" src=\"http:\/\/www.transplantation.com.cn\/wp-content\/uploads\/2024\/10\/image-94.png\" alt=\"\" class=\"wp-image-3529\" style=\"width:750px;height:auto\" srcset=\"https:\/\/www.transplantation.com.cn\/wp-content\/uploads\/2024\/10\/image-94.png 688w, https:\/\/www.transplantation.com.cn\/wp-content\/uploads\/2024\/10\/image-94-300x58.png 300w\" sizes=\"auto, (max-width: 688px) 100vw, 688px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">\u9996\u5148\u6211\u4eec\u5fc5\u987b\u660e\u786e\u4e00\u4e2a\u5171\u8bc6<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u90a3\u5c31\u662f\uff0c\u533b\u751f\u4e0d\u662f\u795e\uff0c\u533b\u751f\u4e0d\u662f\u4e07\u80fd\u7684<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u533b\u751f\u4e0e\u75c5\u9b54\u4e4b\u95f4\uff0c\u4ea6\u5982\u6b66\u4fa0\u8fc7\u62db<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6ca1\u6709100%\u6253\u5305\u7968\u7684\u4e8b<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6bcf\u4e00\u4f4d\u533b\u751f\uff0c\u5c31\u662f\u5c3d\u5168\u529b\u3001\u5c3d\u5168\u529b\u2026\u2026<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u6551\u4eba\uff0c\u6551\u547d<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5173\u4e8e\u80be\u79fb\u690d\u7684\u8fd9\u4e9b\u4e8b\u513f<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6211\u4eec\u6bcf\u5468\u90fd\u4f1a\u5520\u53e8\uff08\u6211\u4eec\u5e0c\u671b\u662f\u666e\u53ca\uff09\u4e00\u4e9b\u76f8\u5173\u8bdd\u9898<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8c22\u8c22\u60a8\u4e00\u76f4\u5728\u7559\u610f\u9605\u8bfb<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6210\u529f\u8bf1\u5bfc<strong>\u80be\u79fb\u690d\u514d\u75ab\u8010\u53d7<\/strong>\uff0c\u8ba9\u80be\u79fb\u690d\u60a3\u8005<strong>\u505c\u7528\u514d\u75ab\u6291\u5236\u5242<\/strong>\uff0c\u662f\u533b\u751f\u548c\u60a3\u8005\u7684\u5171\u540c\u68a6\u60f3, \u4e5f\u662f\u56fd\u9645\u79fb\u690d\u9886\u57df\u6700\u91cd\u8981\u7684\u7814\u7a76\u70ed\u70b9\u4e4b\u4e00\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>&nbsp;\u79fb\u690d\u514d\u75ab\u8010\u53d7\u662f\u4ec0\u4e48\uff1f<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u79fb\u690d\u514d\u75ab\u8010\u53d7<\/strong>\u662f\u6307<strong><em>\u5728\u4e0d\u4f7f\u7528\u514d\u75ab\u6291\u5236\u5242\u7684\u60c5\u51b5\u4e0b\uff0c\u53d7\u8005\u7684\u514d\u75ab\u7cfb\u7edf\u4e0d\u653b\u51fb\u79fb\u690d\u5668\u5b98\uff0c\u5374\u53c8\u4fdd\u6301\u4e86\u5bf9\u5176\u5b83\u5916\u6765\u6297\u539f\u6b63\u5e38\u7684\u514d\u75ab\u5e94\u7b54\u80fd\u529b\u3002<\/em><\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>CAR Treg\u7ec6\u80de<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>\u8c03\u8282\u6027T\u7ec6\u80de\uff08Treg\uff09<\/strong>\u5728\u80be\u79fb\u690d\u672f\u540e\uff0c\u60a3\u8005\u8bf1\u5bfc\u548c\u5efa\u7acb\u514d\u75ab\u8010\u53d7\u8fc7\u7a0b\u4e2d\uff0c\u53d1\u6325\u975e\u5e38\u91cd\u8981\u7684\u4f5c\u7528\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7814\u7a76\u53d1\u73b0\uff0c<strong>\u591a\u6548Treg\u7ec6\u80de\u80fd<\/strong>\u9884<strong>\u9632\u9020\u8840\u5e72\u7ec6\u80de\u79fb\u690d\u540e\u7684\u79fb\u690d\u7269\u6297\u5bbf\u4e3b\u75c5<\/strong>\uff0c\u4f46\u591a\u6548Treg\u7ec6\u80de<strong>\u5c1a\u4e0d\u8db3\u4ee5\u8d77\u5230\u80be\u79fb\u690d\u540e\u9884\u9632\u6392\u65a5\u53cd\u5e94\u7684\u4f5c\u7528<\/strong>\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u8fd1\u671f\u4e00\u9879\u7814\u7a76\u53d1\u73b0\uff0c<strong>\u4f9b\u8005\u7279\u5f02\u6027Treg\u7ec6\u80de\u80fd\u591f\u8d77\u5230\u8bf1\u5bfc\u514d\u75ab\u8010\u53d7\u7684\u4f5c\u7528<\/strong><strong>\u3002<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u7814\u7a76\u8005\u5c06\u53ef\u8bc6\u522b\u4f9b\u8005HLA\u6297\u539f\u7684\u53d7\u4f53\uff0c\u8f6c\u5bfc\u81f3\u53d7\u8005\u5929\u7136\u8c03\u8282\u6027T\u7ec6\u80de\uff08nTreg\uff09\u4e0a\uff0c\u5c06\u5176\u6fc0\u6d3b\u4e3a<strong>CAR Treg\u7ec6\u80de<\/strong>\uff0c\u8fd9\u4e00\u8fc7\u7a0b\u4e0d\u6539\u53d8nTreg\u7ec6\u80de\u7684\u8868\u578b\u53ca\u5176\u9057\u4f20\u7a33\u5b9a\u6027\u3002\u4f46\u662f\uff0c\u4e0enTreg\u7ec6\u80de\u76f8\u6bd4\uff0c<strong>CAR Treg\u7ec6\u80de\u663e\u793a\u51fa\u4e86\u7279\u5f02\u6027\u9488\u5bf9\u4f9b\u8005\u7684\u6781\u5f3a\u7684\u514d\u75ab\u4f4e\u53cd\u5e94\u7684\u80fd\u529b<\/strong>\uff0c\u5b8c\u5168\u9884\u9632\u4e86\u6392\u65a5\u53cd\u5e94\u7684\u53d1\u751f\uff0c\u8fd9\u4e9b\u7ec6\u80de\u5bf9\u4e8e\u8bf1\u5bfc\u548c\u7ef4\u6301\u80be\u79fb\u690d\u514d\u75ab\u8010\u53d7\u6709\u5f88\u91cd\u8981\u7684\u4ef7\u503c\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u590d\u65e6\u5927\u5b66\u9644\u5c5e\u4e2d\u5c71\u533b\u9662\u5728\u80be\u79fb\u690d\u514d\u75ab\u8010\u53d7\u65b9\u9762\u6709\u5f88\u6df1\u5165\u7684\u7814\u7a76\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u5728\u7075\u957f\u7c7b\u52a8\u7269\u98df\u87f9\u7334\u80be\u79fb\u690d\u514d\u75ab\u8010\u53d7\u8bf1\u5bfc\u5de5\u4f5c\u7684\u57fa\u7840\u4e0a\uff0c\u5bf9\u80be\u79fb\u690d\u53d7\u8005\u8fdb\u884c\u5168\u6dcb\u5df4\u653e\u5c04\u7b49\u9884\u5904\u7406\uff0c\u6539\u53d8\u5176\u514d\u75ab\u5fae\u73af\u5883\uff0c\u5e94\u7528\u4f9b\u8005\u9020\u8840\u5e72\u7ec6\u80de\u8f93\u6ce8\u8054\u5408\u80be\u79fb\u690d\u8bf1\u5bfc\u514d\u75ab\u8010\u53d7\uff0c\u53d6\u5f97\u91cd\u8981\u4e34\u5e8a\u8fdb\u5c55\u3002<strong><\/strong><\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p class=\"wp-block-paragraph\"><strong>\u76ee\u524d\u5df2\u7ecf\u5b9e\u65bd\u8be5\u65b9\u6848\u768410\u4f8b\u60a3\u8005\u4e2d\uff1a<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">2\u4f8b\u5df2\u5b8c\u5168\u64a4\u9664\u514d\u75ab\u6291\u5236\u5242\uff0c\u6210\u529f\u6446\u8131\u4e86\u5bf9\u514d\u75ab\u6291\u5236\u5242\u7684\u4f9d\u8d56<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">4\u4f8b\u4ec5\u7528\u5e38\u89c4\u5242\u91cf\u7684\u4e00\u534a<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u90e8\u5206\u60a3\u8005\u5916\u5468\u8840\u548c\u9aa8\u9ad3\u4e2d\u957f\u671f\u5b58\u5728\u4f9b\u53d7\u8005\u5d4c\u5408\u4f53\uff0c\u5d4c\u5408\u7387\u9ad8\u8fbe50%\u3002<\/p>\n<\/blockquote>\n\n\n\n<p class=\"wp-block-paragraph\">\u6211\u4eec\u4ecd\u5728\u4f18\u5316\u514d\u75ab\u8010\u53d7\u65b9\u6848\uff0c\u4e89\u53d6\u4f7f\u66f4\u591a\u7684\u80be\u79fb\u690d\u60a3\u8005\u505c\u7528\u514d\u75ab\u6291\u5236\u5242\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6211\u4eec\u76f8\u4fe1\uff0cCAR Treg\u7ec6\u80de\u5c06\u4e3a\u80be\u79fb\u690d\u514d\u75ab\u8010\u63d0\u4f9b\u91cd\u8981\u7684\u65b0\u601d\u8def\u3002<\/p>\n\n\n\n<div class=\"gspb_button_wrapper gspb_button-id-gsbp-9b0f7c0\" id=\"gspb_button-id-gsbp-9b0f7c0\"><a class=\"wp-block-greenshift-blocks-buttonbox gspb-buttonbox wp-element-button\" href=\"https:\/\/mp.weixin.qq.com\/s\/p5W_ldQXLTXy-XFNqwCQBQ\" title=\"\u5168\u56fd\u9996\u4f8b\u5c3f\u8def\u611f\u67d3\u6cbb\u7597\u6848\u4f8b\" target=\"_blank\" rel=\"noopener\"><span class=\"gspb-buttonbox-textwrap\"><span class=\"gspb-buttonbox-text\"><span class=\"gspb-buttonbox-title\">\u9605\u8bfb\u539f\u6587<\/span><\/span><span class=\"gspb-buttonbox-icon\"><svg class=\"\" style=\"display:inline-block;vertical-align:middle\" width=\"15\" height=\"15\" viewBox=\"0 0 896 1024\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path style=\"fill:#565D66\" d=\"M436.202 76.202l-39.598 39.598c-9.372 9.372-9.372 24.568 0 33.942l310.26 310.258h-682.864c-13.254 0-24 10.746-24 24v56c0 13.254 10.746 24 24 24h682.864l-310.26 310.26c-9.372 9.372-9.372 24.568 0 33.942l39.598 39.598c9.372 9.372 24.568 9.372 33.942 0l418.828-418.828c9.372-9.372 9.372-24.568 0-33.942l-418.83-418.828c-9.372-9.374-24.568-9.374-33.94 0z\"><\/path><\/svg><\/span><\/span><\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u6210\u529f\u8bf1\u5bfc\u80be\u79fb\u690d\u514d\u75ab\u8010\u53d7\uff0c\u8ba9\u80be\u79fb\u690d\u60a3\u8005\u505c\u7528\u514d\u75ab\u6291\u5236\u5242\uff0c\u662f\u533b\u751f\u548c\u60a3\u8005\u7684\u5171\u540c\u68a6\u60f3, \u4e5f\u662f\u56fd\u9645\u79fb\u690d\u9886\u57df\u6700\u91cd\u8981\u7684\u7814\u7a76\u70ed\u70b9\u4e4b\u4e00\u3002<\/p>\n","protected":false},"author":1,"featured_media":3620,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_gspb_post_css":"#gspb_button-id-gsbp-9b0f7c0{display:flex;justify-content:center}#gspb_button-id-gsbp-9b0f7c0 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