{"id":526,"date":"2024-07-15T15:53:57","date_gmt":"2024-07-15T07:53:57","guid":{"rendered":"http:\/\/zhongshan.wordpress.aibingliben.com\/?p=526"},"modified":"2025-03-25T10:01:47","modified_gmt":"2025-03-25T02:01:47","slug":"%e6%8f%ad%e7%a7%98hla%ef%bc%9a%e4%ba%b2%e5%b1%9e%e8%82%be%e7%a7%bb%e6%a4%8d%e6%88%90%e5%8a%9f%e7%9a%84%e5%85%b3%e9%94%ae%e5%af%86%e7%a0%81","status":"publish","type":"post","link":"https:\/\/www.transplantation.com.cn\/en_US\/2024\/07\/15\/%e6%8f%ad%e7%a7%98hla%ef%bc%9a%e4%ba%b2%e5%b1%9e%e8%82%be%e7%a7%bb%e6%a4%8d%e6%88%90%e5%8a%9f%e7%9a%84%e5%85%b3%e9%94%ae%e5%af%86%e7%a0%81\/","title":{"rendered":"Unraveling the secret of HLA: the key to successful kidney transplantation"},"content":{"rendered":"\n<p class=\"has-text-color has-link-color wp-elements-d9ea0c222f9b9ec42e51510b94494455 wp-block-paragraph\" style=\"color:#3e454e;font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);line-height:2.1\">Relative kidney transplantation is a way to greatly improve the success rate and survival rate of kidney transplantation, but finding a kidney that matches the recipient still needs to overcome the difficulties of human immunity, one of them, General who guards the pass, is our main character today, HLA. HLA, or Human Leukocyte Antigen, is a group of cell-surface antigens encoded by a complex of genes located in the Human chromosome 6 Human Leukocyte Antigen. It is also an important antigen that causes kidney transplant rejection<\/p>\n\n\n\n<p class=\"has-text-color has-link-color wp-elements-72ebfb1eff8215c899c261f58ef9a089 wp-block-paragraph\" style=\"color:#3e454e;font-size:clamp(14px, 0.875rem + ((1vw - 3.2px) * 0.313), 18px);line-height:2.1\">If the HLA match does not match, the recipient&#8217;s immune system may see the new kidney as a foreign invader and launch an attack.This is the transplant rejection. HLA-induced rejection mainly involves immune cell-mediated rejection and antibody-mediated rejection.<\/p>\n\n\n\n<div class=\"gspb_button_wrapper gspb_button-id-gsbp-9b0f7c0\" id=\"gspb_button-id-gsbp-9b0f7c0\"><a class=\"wp-block-greenshift-blocks-buttonbox gspb-buttonbox wp-element-button\" href=\"https:\/\/mp.weixin.qq.com\/s\/rgAuxBUpMFmpXHb3CgzprQ\" title=\"\u4e0b\u5217\u4eba\u7269\u5173\u7cfb\u4e2d\uff0c\u53ef\u4ee5\u8fdb\u884c\u6d3b\u4f53\u4eb2\u5c5e\u4f9b\u80be\u79fb\u690d\u7684\u662f\uff1f\" target=\"_blank\" rel=\"noopener\"><span class=\"gspb-buttonbox-textwrap\"><span class=\"gspb-buttonbox-text\"><span class=\"gspb-buttonbox-title\">Read the original article<\/span><\/span><span class=\"gspb-buttonbox-icon\"><svg class=\"\" style=\"display:inline-block;vertical-align:middle\" width=\"15\" height=\"15\" viewBox=\"0 0 896 1024\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path style=\"fill:#565D66\" d=\"M436.202 76.202l-39.598 39.598c-9.372 9.372-9.372 24.568 0 33.942l310.26 310.258h-682.864c-13.254 0-24 10.746-24 24v56c0 13.254 10.746 24 24 24h682.864l-310.26 310.26c-9.372 9.372-9.372 24.568 0 33.942l39.598 39.598c9.372 9.372 24.568 9.372 33.942 0l418.828-418.828c9.372-9.372 9.372-24.568 0-33.942l-418.83-418.828c-9.372-9.374-24.568-9.374-33.94 0z\"><\/path><\/svg><\/span><\/span><\/a><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p><!-- wp:paragraph {\"style\":{\"typography\":{\"fontSize\":\"18px\",\"lineHeight\":\"2.1\"},\"elements\":{\"link\":{\"color\":{\"text\":\"#3e454e\"}}},\"color\":{\"text\":\"#3e454e\"}}} --><\/p>\n<p class=\"has-text-color has-link-color\" style=\"color:#3e454e;font-size:18px;line-height... \n\n","protected":false},"author":1,"featured_media":528,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_gspb_post_css":"#gspb_button-id-gsbp-9b0f7c0{display:flex;justify-content:center}#gspb_button-id-gsbp-9b0f7c0 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