{"id":3647,"date":"2024-10-28T14:13:20","date_gmt":"2024-10-28T06:13:20","guid":{"rendered":"https:\/\/www.transplantation.com.cn\/?p=3647"},"modified":"2025-04-01T17:33:29","modified_gmt":"2025-04-01T09:33:29","slug":"%e6%9c%80%e6%96%b0%e7%a0%94%e7%a9%b6%e8%af%81%e5%ae%9e%ef%bc%8c%e8%a1%80%e8%84%82%e9%ab%98%e4%bc%9a%e5%a2%9e%e5%8a%a0%e6%8e%92%e6%96%a5%e9%a3%8e%e9%99%a9%ef%bc%81","status":"publish","type":"post","link":"https:\/\/www.transplantation.com.cn\/en_US\/2024\/10\/28\/%e6%9c%80%e6%96%b0%e7%a0%94%e7%a9%b6%e8%af%81%e5%ae%9e%ef%bc%8c%e8%a1%80%e8%84%82%e9%ab%98%e4%bc%9a%e5%a2%9e%e5%8a%a0%e6%8e%92%e6%96%a5%e9%a3%8e%e9%99%a9%ef%bc%81\/","title":{"rendered":"New Research Confirms That High Blood Lipids Can Increase the Risk of Rejection!"},"content":{"rendered":"\n<p><strong>October 28, 2024, Immune Tolerance<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"688\" height=\"134\" src=\"http:\/\/www.transplantation.com.cn\/wp-content\/uploads\/2024\/10\/image-94.png\" alt=\"\" class=\"wp-image-3529\" style=\"width:750px;height:auto\" srcset=\"https:\/\/www.transplantation.com.cn\/wp-content\/uploads\/2024\/10\/image-94.png 688w, https:\/\/www.transplantation.com.cn\/wp-content\/uploads\/2024\/10\/image-94-300x58.png 300w\" sizes=\"auto, (max-width: 688px) 100vw, 688px\" \/><\/figure>\n\n\n\n<p>Hyperlipidemia is highly prevalent among kidney transplant recipients. The causes may include genetic factors, high-fat diets, and the use of immunosuppressants.<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"446\" height=\"327\" src=\"https:\/\/www.transplantation.com.cn\/wp-content\/uploads\/2024\/10\/image-121.png\" alt=\"\" class=\"wp-image-3650\" srcset=\"https:\/\/www.transplantation.com.cn\/wp-content\/uploads\/2024\/10\/image-121.png 446w, https:\/\/www.transplantation.com.cn\/wp-content\/uploads\/2024\/10\/image-121-300x220.png 300w\" sizes=\"auto, (max-width: 446px) 100vw, 446px\" \/><\/figure>\n\n\n\n<p><strong>Latest Research<\/strong><br \/>The Tufts University research team recently published their findings on the relationship between hyperlipidemia and organ rejection in the <em>American Journal of Transplantation<\/em>. The findings indicate that hyperlipidemia (primarily elevated triglycerides and cholesterol) may increase the risk of rejection by modulating the immune system. Traditional immunological theory does not associate rejection with hyperlipidemia. This study found that hyperlipidemia can alter the levels of Th17 cells and Treg cells in the body, increasing the risk of organ transplant rejection, thereby enhancing the relevant theories of organ transplant rejection.<\/p>\n\n\n\n<figure class=\"wp-block-image aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"603\" height=\"414\" src=\"https:\/\/www.transplantation.com.cn\/wp-content\/uploads\/2024\/10\/image-120.png\" alt=\"\" class=\"wp-image-3649\" srcset=\"https:\/\/www.transplantation.com.cn\/wp-content\/uploads\/2024\/10\/image-120.png 603w, https:\/\/www.transplantation.com.cn\/wp-content\/uploads\/2024\/10\/image-120-300x206.png 300w\" sizes=\"auto, (max-width: 603px) 100vw, 603px\" \/><\/figure>\n\n\n\n<p><strong>Key Considerations<\/strong><br \/>This study highlights that long-term follow-up after kidney transplantation necessitates blood lipid testing. Hyperlipidemia not only harms the cardiovascular system but also directly elevates the risk of rejection! Focus on maintaining a healthy lifestyle, such as adhering to a low-fat diet, controlling body weight, and engaging in regular exercise. When necessary, supplement with lipid-lowering medications. Currently, the most commonly used oral lipid-lowering medications in clinical practice include atorvastatin (Lipitor), simvastatin (Zocor), rosuvastatin (Crestor), and pravastatin (Pravachol), among others.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"798\" height=\"282\" src=\"https:\/\/www.transplantation.com.cn\/wp-content\/uploads\/2024\/10\/image-119.png\" alt=\"\" class=\"wp-image-3648\" srcset=\"https:\/\/www.transplantation.com.cn\/wp-content\/uploads\/2024\/10\/image-119.png 798w, https:\/\/www.transplantation.com.cn\/wp-content\/uploads\/2024\/10\/image-119-300x106.png 300w, https:\/\/www.transplantation.com.cn\/wp-content\/uploads\/2024\/10\/image-119-768x271.png 768w\" sizes=\"auto, (max-width: 798px) 100vw, 798px\" \/><\/figure>\n\n\n\n<p><strong>Dr. Jia Concludes<\/strong><br \/>Hyperlipidemia is a significant adverse factor impacting the health of kidney transplant recipients. Previously, we focused on its adverse effects on the cardiovascular system, but the latest research demonstrates that elevated blood lipids increase the risk of rejection. Therefore, it is highly necessary for kidney transplant patients to consistently monitor blood lipid levels, maintain a healthy lifestyle, and, if needed, use lipid-lowering medications to strictly control blood lipid levels.<\/p>\n\n\n\n<p><strong>Written by | Jia Yichen, Edited by | Qi Guisheng, Homepage Image Sourced from the Internet<\/strong><\/p>\n\n\n\n<div class=\"gspb_button_wrapper gspb_button-id-gsbp-9b0f7c0\" id=\"gspb_button-id-gsbp-9b0f7c0\"><a class=\"wp-block-greenshift-blocks-buttonbox gspb-buttonbox wp-element-button\" href=\"https:\/\/mp.weixin.qq.com\/s\/MsHSLsscs0UCxWkDcloRBw\" title=\"\u5168\u56fd\u9996\u4f8b\u5c3f\u8def\u611f\u67d3\u6cbb\u7597\u6848\u4f8b\" target=\"_blank\" rel=\"noopener\"><span class=\"gspb-buttonbox-textwrap\"><span class=\"gspb-buttonbox-text\"><span class=\"gspb-buttonbox-title\">Read the original article<\/span><\/span><span class=\"gspb-buttonbox-icon\"><svg class=\"\" style=\"display:inline-block;vertical-align:middle\" width=\"15\" height=\"15\" viewBox=\"0 0 896 1024\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path style=\"fill:#565D66\" d=\"M436.202 76.202l-39.598 39.598c-9.372 9.372-9.372 24.568 0 33.942l310.26 310.258h-682.864c-13.254 0-24 10.746-24 24v56c0 13.254 10.746 24 24 24h682.864l-310.26 310.26c-9.372 9.372-9.372 24.568 0 33.942l39.598 39.598c9.372 9.372 24.568 9.372 33.942 0l418.828-418.828c9.372-9.372 9.372-24.568 0-33.942l-418.83-418.828c-9.372-9.374-24.568-9.374-33.94 0z\"><\/path><\/svg><\/span><\/span><\/a><\/div>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p><!-- wp:paragraph --><\/p>\n<p><strong>October 28, 2024, Immune Tolerance<\/strong><\/p>\n<p><!-- \/wp:paragraph --><\/p>\n<p><!-- wp:image {\"id\":3529,\"width\":\"750px\",\"height\":\"auto\",\"sizeSlug\":\"full\",\"linkDestination\":\"none\",\"align\":\"center\"} --><\/p>\n<figure class=\"wp-block... \n\n","protected":false},"author":1,"featured_media":3651,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_gspb_post_css":"#gspb_button-id-gsbp-9b0f7c0{display:flex;justify-content:center}#gspb_button-id-gsbp-9b0f7c0 .gspb-buttonbox-text{display:flex;flex-direction:column}#gspb_button-id-gsbp-9b0f7c0>.gspb-buttonbox{box-sizing:border-box}#gspb_button-id-gsbp-9b0f7c0>.gspb-buttonbox>.gspb-buttonbox-textwrap>.gspb-buttonbox-icon{display:flex}#gspb_button-id-gsbp-9b0f7c0>.gspb-buttonbox .gspb-buttonbox-icon svg,#gspb_button-id-gsbp-9b0f7c0>.gspb-buttonbox .gspb-buttonbox-icon svg path,#gspb_button-id-gsbp-9b0f7c0>.gspb-buttonbox:hover .gspb-buttonbox-icon svg,#gspb_button-id-gsbp-9b0f7c0>.gspb-buttonbox:hover .gspb-buttonbox-icon svg path{fill:#fff!important}#gspb_button-id-gsbp-9b0f7c0>.gspb-buttonbox .gspb-buttonbox-icon svg{margin:0!important}#gspb_button-id-gsbp-9b0f7c0>.gspb-buttonbox>.gspb-buttonbox-textwrap{display:flex;flex-direction:row;align-items:center}#gspb_button-id-gsbp-9b0f7c0 .gspb-buttonbox-icon{margin-left:13px}#gspb_button-id-gsbp-9b0f7c0>.gspb-buttonbox{margin-bottom:0;background-color:#226dc2;cursor:pointer;text-decoration:none;color:#fff;border-style:solid;border-width:1px;border-color:#428ad6;box-shadow:0 2px 4px 0 #0000001a}#gspb_button-id-gsbp-9b0f7c0>.gspb-buttonbox a{text-decoration:none}#gspb_button-id-gsbp-9b0f7c0>.gspb-buttonbox,#gspb_button-id-gsbp-9b0f7c0>.gspb-buttonbox>.gspb_backgroundOverlay{border-top-left-radius:4px;border-top-right-radius:4px;border-bottom-right-radius:4px;border-bottom-left-radius:4px}#gspb_button-id-gsbp-9b0f7c0>.gspb-buttonbox:hover{box-shadow:0 3px 9px 0 #12121226;transform:translateY(-2px)}#gspb_button-id-gsbp-9b0f7c0>.gspb-buttonbox,#gspb_button-id-gsbp-9b0f7c0>.gspb-buttonbox .gspb-buttonbox-icon svg,#gspb_button-id-gsbp-9b0f7c0>.gspb-buttonbox .gspb-buttonbox-icon svg path{transition:all .25s cubic-bezier(.165,.84,.44,1)}#gspb_button-id-gsbp-9b0f7c0>.gspb-buttonbox:active,.active #gspb_button-id-gsbp-9b0f7c0>.gspb-buttonbox{transform:translateY(2px)}","footnotes":""},"categories":[103],"tags":[],"class_list":["post-3647","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-103"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/www.transplantation.com.cn\/en_US\/wp-json\/wp\/v2\/posts\/3647","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.transplantation.com.cn\/en_US\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.transplantation.com.cn\/en_US\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.transplantation.com.cn\/en_US\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.transplantation.com.cn\/en_US\/wp-json\/wp\/v2\/comments?post=3647"}],"version-history":[{"count":2,"href":"https:\/\/www.transplantation.com.cn\/en_US\/wp-json\/wp\/v2\/posts\/3647\/revisions"}],"predecessor-version":[{"id":7039,"href":"https:\/\/www.transplantation.com.cn\/en_US\/wp-json\/wp\/v2\/posts\/3647\/revisions\/7039"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.transplantation.com.cn\/en_US\/wp-json\/wp\/v2\/media\/3651"}],"wp:attachment":[{"href":"https:\/\/www.transplantation.com.cn\/en_US\/wp-json\/wp\/v2\/media?parent=3647"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.transplantation.com.cn\/en_US\/wp-json\/wp\/v2\/categories?post=3647"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.transplantation.com.cn\/en_US\/wp-json\/wp\/v2\/tags?post=3647"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}